It’s all in the name, Research. We are Sepsis Research, and our main objective is to #StopSepsisNow by helping fund essential medical research into the disease.

Thanks to your generous donations, we are now co-funding pioneering research being undertaken at the world-leading Roslin Institute.

Our initial focus was looking at the role that genes play in how likely people are to die from Sepsis, to help speed up the search for new treatments. Now, with the rapidly spreading global pandemic, COVID-19, the team have been asked to use the infrastructure created for Sepsis Research, to help provide important answers to the questions on this disease to aid in the fight against it.

What we’re doing to support the fight against COVID-19

Thanks to additional government funding (£4.9million), the team at the Roslin Institute are able to start a new study into this strand of Coronavirus, COVID-19 and work to learn more about the disease and how to combat it. The team will work to collect samples and data from patients with confirmed cases to learn more about the disease and provide real-time updates and information which can be used to help control the outbreak and establish treatment options.

We’re incredibly proud that our partnership with the institute, will allow the team to jump start the research into COVID-19. Over the next year, the institute will recruit a minimum of 1,300 patients to begin their research. Results will be processed and released as soon as possible to help combat the spread of the disease, researchers hope within months.

This is why now, more than ever, we need your help. We need your help to support the team in their work combatting this disease, and continuing to support our work to invest more into research into Sepsis in the future. If you’re able to spare a contribution of any size, big or small, it will go a long way, click here to donate.

What we’re doing to support the fight against Sepsis

While this awful disease and the news surrounding it has been sweeping the nation, we’ve wanted to do what we can to help, but have not forgotten our purpose, to help stop sepsis. Our focus for the future is to keep striving towards a better understanding of the disease and the symptoms, so we can reduce the number of deaths from sepsis, to zero. We’re working hard, and with your generous donations and fundraising activity, are supporting the institute with the GenOMICC Study.

The GenOMICC Study being led by Dr Kenneth Baillie, Academic Consultant in Critical Care Medicine and Group Leader at the University of Edinburgh’s Roslin Institute, is a worldwide study which will involve clinicians capturing 100,000 DNA samples from patients in intensive care and high dependency units. In the UK there are over 50 hospitals already taking part and over 1000 intensive care beds, all taking blood and tissue samples which are sent for analysis at The Roslin Institute.

The researchers are comparing the DNA from those who survive sepsis with those who die from the condition to unlock clues to help #StopSepsisNow. For example, what genetic factors may make someone more likely to become critically ill, and which may alter their chance of survival, especially if they’d previously been in good health.

Research has already shown that people who have been adopted are six times more likely to die from infection if their biological parents died of infection; yet the same is not seen with adoptive parents. This suggests that genes are key to us understanding more about sepsis.

New estimates show that twice as many people are dying from sepsis worldwide than previously estimated, so there’s never been a more urgent time to help find a cure for sepsis:

  • One in every five deaths worldwide are associated with sepsis
  • Two out of every five cases are in children under five

Research is expensive. Significant funding is required to provide our researchers and support staff with the resources needed to carry out their vital work. If you would like to help, there are many ways to get involved in fundraising.

Sepsis Research previously offered small grant funding through The FEATURES Awards but these are now closed as we focus on our research partnership with the Roslin Institute.  By focusing our efforts to one major partnership, we feel we can do more to help fight against this disease.

Spifox Monitors

Sepsis Research (FEAT) and Spifox combined to donate six monitors to the Royal Hospital for Children in Glasgow. The monitors support measurements of the Paediatric Early Warning Scores (PEWS). They are used in 2 acute wards to measure vital signs such as heart rate, respiratory rate, blood pressure and oxygen saturations. Repeated measurement of these vital signs helps to detect deterioration over time, which may indicate sepsis. The early appreciation of changes allows faster detection, response and treatment in the management of sepsis.

The monitors were accepted on behalf of the hospital by Senior Staff Nurse Sharon Pate who said: “In a very busy paediatric word it is vital all our patients are monitored regularly and closely for signs of deterioration. The addition of these new monitors will greatly improve our ability to monitor patients and provide vital care.”